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GER-AUG: Augsburg

Contributors from the MPC: Angela Döring and Christa Meisinger


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© National Institute for Health and Welfare and the MORGAM Project investigators
Last updated: 19 May 2010
For more information, please contact Kari Kuulasmaa (firstname.lastname@thl.fi)

Contents


Cohort identification

Cohort recruitment and the baseline examination

The cohorts were formed by the respondents of representative sample surveys of the RUs. List of municipalities and population registers were used as sampling frames for the first and the second stage of two-stage sampling, respectively. The second stage of the sampling was stratified by sex and 10-year age group. The baseline examinations were carried out as part of the WHO MONICA Project, where they were recognized by codes GER-AURa (RU 02) and GER-AUUa (RU 01). RU 03 of MORGAM combines RUs 01 and 02 of MONICA. Follow-up studies were conducted in the frame of the Cooperative Research in the Study region of Augsburg (KORA).

The size of the MORGAM cohorts and the response rates of the population surveys from which the cohorts were derived are:

RUA Cohort Men Women Total Response rate
GER-AUGa 01 2004 1976 3980 79%
02 2341 2298 4639 76%
03 2269 2211 4480 74%
Total 6614 6485 13099  

DNA are available for about 80% of the participants of all three cohorts.

End-points followed up:

End of follow-up period:

Follow-up procedures

Sources of data

Procedures

Within the framework of the KORA Study, a follow-up questionnaire was sent to each former participant in 1997-1998 and in 2002-2003 to obtain information on the occurrence of chronic diseases and risk factors.

Mortality follow-up: If a person did not return the follow-up questionnaire, the person's vital status was ascertained through the Population Registers inside and outside the study area. Record linkage was based on name, sex, date of birth and address. If the person has died the information on when and where is provided by the Population Registers and a copy of death certificate is obtained from the Regional Health Department. If the person has moved out of the study area the time of move and usually the information on the new address is available. The vital status could not be assessed for those who had moved to a foreign country or to an unknown location in the country.

Follow-up of CHD events: Each time a non-fatal event was entered to the Coronary Event Register, it was linked to the Cohorts using name and date of birth. All deaths in the Cohorts were linked to the Coronary Event Register using the dates of birth and death. If a person has moved out of the study area, information from the follow-up questionnaire was used and General Practitioner's notes and hospital discharge letters were gathered. If such a person did not return the questionnaire, the date of moving outside the study area is known through the Population Registers and the date of loss to follow-up for non-fatal events was the date of moving. Non-fatal events were not followed up for those who had a self-reported MI at baseline.

Diagnostic procedures

At baseline:

During follow-up:

References

  1. Löwel H, Lewis M, Hörmann A, Keil U. Case finding, data quality aspects and comparability of myocardial infarction registers: Results of a south German register study. J Clin Epidemiol. 1991;44(3):249-260.
  2. Keil U, Liese AD, Hense HW, Filipiak B, Doring A, Stieber J, Lowel H. Classical risk factors and their impact on incident non-fatal and fatal myocardial infarction and all-cause mortality in southern Germany. Results from the MONICA Augsburg cohort study 1984-1992. Monitoring Trends and Determinants in Cardiovascular Diseases. Eur Heart J. 1998;19(8):1197-207.

Updates to this document

Date Update
2006-05-14 Date of the first published version.
2008-01-18 The name of the Administrative centre and the list of Key personnel was updated.
2010-05-19 The baseline age range of Cohorts 02 and 03 was extended from 64 years to 74 years, and the cohort description was updated accordingly.

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